How Much Does Tagrisso (Osimertinib) Cost? | OnlineMeds
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Oncology Clinically reviewed 2 min read

How Much Does Tagrisso (Osimertinib) Cost? Price & Generic Options

What Tagrisso (osimertinib) actually costs by country, why it is so expensive, and how the generic changes the picture.

AS
A. Srinivasan B.Pharm, M.Pharm
Updated Jul 8, 2026
How Much Does Tagrisso (Osimertinib) Cost? Price & Generic Options
For information only. This article does not replace medical advice. Always consult a licensed healthcare professional before starting, changing, or stopping any medication.

Tagrisso (osimertinib) is a highly effective targeted therapy for EGFR-mutation-positive non-small cell lung cancer — and one of the most expensive medicines a patient can be prescribed. If you are facing the cost out of pocket, here is what it actually costs and where the savings are.

How much does Tagrisso cost?

Pricing varies enormously by country and insurance, but indicatively the branded originator costs around US$18,000 per month in the United States, roughly £5,000 in the UK, and about A$8,000 in Australia before any subsidy. Over a year of continuous treatment, that runs into six figures.

Why is Tagrisso so expensive?

Tagrisso is protected by patents, so there is little price competition. The originator price reflects the cost of the research, clinical trials and global marketing that brought osimertinib to market — costs the manufacturer recovers during the patent-protected period.

Tagrisso cost without insurance

Without insurance or a reimbursement scheme, the full list price falls on the patient. For many people this is simply unaffordable, which is why patients and carers search for lower-cost routes — patient-assistance programmes, and above all the generic.

How to pay less: generic Osimertinib

The single biggest lever on cost is the generic. Generic Osimertinib contains the same active ingredient as branded Tagrisso, produced by licensed pharmaceutical manufacturers, typically at a small fraction of the originator price. See the full side-by-side breakdown, strengths and current pricing on our generic Tagrisso (Osimertinib) page, or browse all Osimertinib products. A valid prescription is required and every order is reviewed by a licensed pharmacist before dispatch. Used as prescribed by a licensed medical professional.

Frequently asked questions

How much does Tagrisso cost per month?

Branded Tagrisso is one of the most expensive oncology medicines — indicatively around US$18,000 a month in the United States, roughly £5,000 in the UK and about A$8,000 in Australia before any subsidy or insurance. Exact prices vary widely.

Why is Tagrisso so expensive?

It is a patent-protected, targeted cancer therapy. The originator price reflects research, trials and marketing costs under patent protection, with little price competition until generics arrive.

Is there a generic version of Tagrisso?

Yes. Generic osimertinib contains the same active ingredient at the same 40 mg and 80 mg strengths, produced by licensed pharmaceutical manufacturers.

How much cheaper is generic osimertinib?

Generic osimertinib is typically a small fraction of the branded price. Exact savings depend on country and pack size — see our generic Tagrisso page for current pricing.

This article is general information, not medical or financial advice. Prices are indicative and vary by country, pack size, insurance and over time. Always use any medicine as prescribed by a licensed medical professional.

AS
Written by
A. Srinivasan

A. Srinivasan is a licensed clinical pharmacist with 24 years of experience. He holds a B.Pharm and M.Pharm from University of Madras. At OnlineMeds, he reviews medicine and health content to help ensure it is accurate, evidence-based, and easy to understand.

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