Cyclophil Me 100mg Capsule
Cyclophil Me 100mg Capsule is a trusted medication containing Active Pharmaceutical Ingredient, designed for personal use under the guidance of a healthcare professional. Available for prescription-based international supply with discreet worldwide delivery.
- Active ingredient: Cyclosporine
- Form: Capsule
- Indication: Transplant rejection prophylaxis; severe rheumatoid arthritis; severe psoriasis; nephrotic syndrome
- Manufacturer: CYCLOPHIL ME 100
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What is Cyclosporine?
How Does It Work?
Cyclosporine binds the cytoplasmic protein cyclophilin A, forming a drug-protein complex inside T cells.
The cyclosporine-cyclophilin complex inhibits calcineurin, a phosphatase that normally activates NFAT transcription factors in T lymphocytes.
Without calcineurin activity, NFAT cannot enter the nucleus, so T cells fail to produce IL-2 and cannot proliferate in response to alloantigens — preventing rejection and autoimmune inflammation.
How to Use
Side Effects & Precautions
- Nephrotoxicity (dose-dependent)
- Hypertension
- Tremor
- Hirsutism
- Gingival hyperplasia
- Hyperkalaemia
- Chronic nephrotoxicity (cumulative kidney damage)
- Hypertension requiring antihypertensive treatment
- Lymphoma and skin malignancies
- Neurotoxicity (encephalopathy, seizures at high levels)
- Uncontrolled hypertension or active infections (non-transplant use)
- Concurrent potassium-sparing diuretics (hyperkalaemia risk)
- Concurrent nephrotoxic drugs without close monitoring
Generic vs Brand
Storage & Handling
Why Buy From Us
Sourced directly from licensed pharmaceutical manufacturers.
Every batch tested for purity and bioequivalence.
Discreet shipping to UK, US, AU, EU and beyond.
Regulated and compliant with international pharmacy standards.
Frequently Asked Questions
Nephrotoxicity and hepatotoxicity — use only under supervision of physicians experienced in immunosuppressive therapy and organ transplant management.
Increased susceptibility to infection and lymphoma with concurrent immunosuppressants.
Drug Interactions
| Drug / Substance | Effect | Action |
|---|---|---|
| Nephrotoxic drugs (aminoglycosides, NSAIDs — additive kidney damage) | ||
| CYP3A4 inhibitors (ketoconazole, diltiazem — increase cyclosporine levels) | ||
| CYP3A4 inducers (rifampicin, carbamazepine — reduce levels) | ||
| Statins (increased myopathy risk) | ||
| Grapefruit juice (increases cyclosporine levels) | ||