Generic Sustiva (Efavirenz) — Same Medicine, 91% Less

FDA-approved Efavirenz — the generic equivalent of Sustiva. Used for HIV-1 treatment. Same active ingredient, same efficacy, dramatically lower cost.

Reviewed by a licensed pharmacist.

Sustiva vs Generic Efavirenz

Sustiva (Brand) Generic (Efavirenz)
Active Ingredient Efavirenz Efavirenz
Strength 600mg tablets 600mg tablets
Manufacturer Bristol Myers Squibb Natco / Cipla / Aurobindo
Avg. Monthly Cost (USA) ~$1,200 ~$108
FDA Therapeutic Equivalent

Available Generic Efavirenz Products

Browse our selection of generic Efavirenz 600mg tablets. All products are from WHO-GMP certified manufacturers.

View all Efavirenz products →

Is Generic Efavirenz Safe?

Generic Efavirenz is bioequivalent to Sustiva. It contains the identical active ingredient at the same concentration, undergoes the same rigorous FDA/EMA testing, and works identically in the body. Generic approval requires proof of bioequivalence — meaning the medicine performs the same way as the brand.

Efavirenz is a well-established HIV NNRTI (non-nucleoside reverse transcriptase inhibitor) that has been used successfully for over 25 years. The generic has identical efficacy and side-effect profile.

All OnlineMeds generics are manufactured in WHO-GMP certified facilities in India, which supplies 40% of all generic medicines used in the US and approved by the FDA.

How to Order

  1. Add your medicine to cart
  2. Create your account at checkout
  3. Upload your prescription (required for this Rx medicine)
  4. Our pharmacist verifies your order within 24 hours
  5. Shipped discreetly in 7–14 business days

Learn more about our ordering process →

Frequently Asked Questions

Is generic Efavirenz as effective as Sustiva?

Yes. Generic Efavirenz contains the identical active ingredient and concentration as Sustiva. Bioequivalence testing proves both medicines work the same way in the body for HIV treatment.

Why is generic Efavirenz so much cheaper?

Generic manufacturers don’t bear the research and development costs of discovering the drug. Sustiva’s development cost Bristol Myers Squibb over $500 million. Generics skip this cost and pass savings to patients.

Is a prescription required for Efavirenz?

Yes. Efavirenz is a prescription-only medicine used for HIV treatment. A valid prescription from an HIV specialist or physician is required.

Are there side effects I should know about?

Efavirenz can cause dizziness or neurological symptoms in some patients, especially when first starting. These typically resolve within 2–4 weeks. The generic has the same side-effect profile as the brand. Discuss with your physician if you have concerns.

Where is generic Efavirenz manufactured?

Our generic Efavirenz is manufactured in WHO-GMP certified facilities in India. These facilities are approved by the FDA, EMA, and WHO for producing medicines used worldwide.

How much can I save with generic Efavirenz?

Sustiva typically costs $1,200 per month in the USA. Generic Efavirenz costs approximately $108 per month on OnlineMeds — a saving of 91%.

This content is for informational purposes only and does not constitute medical advice. Always use Efavirenz as prescribed by your HIV specialist or physician. OnlineMeds is not a substitute for professional medical consultation.