Generic Xtandi (Enzalutamide)
Same active ingredient — enzalutamide — as Xtandi®, at a substantially lower price. Produced by licensed pharmaceutical manufacturers.
The same active ingredient, without the originator price
Generic enzalutamide is the equivalent of branded Xtandi® — not a different medicine, and not a “knockoff.”
Any switch between brand and generic should be discussed with your prescribing doctor. Reference prices are indicative public list prices and vary by market.
What Xtandi® typically costs — and the generic alternative
Typical branded reference prices by market, next to our generic enzalutamide price.
| Market | Branded Xtandi® — reference price | Generic enzalutamide — OnlineMeds |
|---|---|---|
| United States | ~$14,000+ / month (brand) branded list price |
|
| United Kingdom | ~£2,700 / month branded list price |
|
| Australia | ~A$4,000 / month branded list price |
Reference prices are indicative public list prices for the originator brand. Prices vary by destination & quantity — not a promised discount.
Enzalutamide, explained simply
Written and reviewed by our pharmacist team. Informational only — your doctor directs your treatment.
Enzalutamide is the active ingredient in Xtandi®, an androgen receptor inhibitor used in prostate cancer. Generic enzalutamide contains the same active ingredient at the same strengths and is produced by licensed pharmaceutical manufacturers, typically far below the originator price. Used as prescribed by a licensed medical professional.
Xtandi® is the originator brand for enzalutamide, developed by Astellas and Pfizer. It is prescribed in the management of certain stages of prostate cancer. It is a prescription-only specialist medicine taken by mouth.
Enzalutamide is an androgen receptor inhibitor. It blocks the action of androgens (such as testosterone) that can drive the growth of prostate-cancer cells. It is used as part of a treatment plan directed by your oncologist or urologist.
Enzalutamide is prescribed for adult men with specific stages of prostate cancer, as determined by a specialist based on diagnosis and overall health.
Enzalutamide is usually taken once daily, with or without food, swallowed whole with water at about the same time each day. Your specialist sets the dose and may adjust it for side effects. Tell your doctor about all medicines you take, as interactions are possible.
Never change your dose on your own.
Reported side effects of enzalutamide may include tiredness, hot flushes, high blood pressure, headache, and, less commonly, seizures or falls. Report fainting or seizures promptly. Your specialist monitors blood pressure during treatment. This is not a complete list.
Report new or worsening symptoms to your doctor promptly. This is not a complete list — see the patient information leaflet.
Store as directed on the patient information leaflet, usually at room temperature away from moisture and out of reach of children. Always follow the storage guidance supplied with your medicine.
Xtandi® vs generic enzalutamide
| Attribute | Xtandi® (brand) | Generic enzalutamide |
|---|---|---|
| Active ingredient | Enzalutamide | Enzalutamide Same |
| Strengths | 40 mg capsule; 40 / 80 mg tablet | Same |
| Dosage form | Capsule / tablet | Capsule / tablet Same |
| Originator | Astellas / Pfizer | Licensed manufacturer |
| Prescription required | Yes | Yes Same |
| Typical cash price | ~$14,000+ / month (brand) (United States reference) | |
| Availability | National pharmacies & insurance coverage | Ships worldwide from OnlineMeds — Rx required |
Equivalence refers to the active ingredient, strength, and form. Discuss any switch with your prescribing doctor.
A pharmacy, not a marketplace
Every order is sourced, checked, and dispatched by our own licensed pharmacy team.
Frequently asked questions
Quick answers about equivalence, prescriptions, legality, and delivery. Tap a question to expand.
Is generic enzalutamide the same as Xtandi?
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How long does delivery take?
Sitharam Reddy is a licensed clinical pharmacist with 19 years of experience. He holds a B.Pharm and M.Pharm from Rajiv Gandhi University of Health Sciences. At OnlineMeds, he reviews medicine and health content to help ensure it is accurate, evidence-based, and easy to understand.
Informational only. Used as prescribed by a licensed medical professional. This content is for informational purposes only and does not replace advice from your doctor or pharmacist. Consult a healthcare professional before use.
This page draws on public information from recognised health authorities and cancer organisations. Always follow the guidance of your own doctor.