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Prescription only medicine

Abiraxen 250mg Tablets

Abiraterone Acetate 250 mg · Generic equivalent of Zytiga

Abiraxen 250mg Tablets is a trusted medication containing Abiraterone, designed for personal use under the guidance of a healthcare professional. Available for prescription-based international supply with discreet worldwide delivery.

Active ingredient
Abiraterone Acetate
Strength
250 mg
Form
Tablet
Manufacturer
Everest Pharmaceuticals Ltd.
Made in
Bangladesh
Prescription
Required
Commonly used forCancer

Generic equivalent of Zytiga — up to 80% less than the branded price

Our oncology team reviews every request personally and responds within 24 hours.
Verified pharmacy Genuine medication Tracked shipping Medically reviewed by A. Srinivasan
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Dedicated Oncology Team Doctor + pharmacist review every order before dispatch
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About this medicine

What is Abiraxen 250mg Tablets?

Abiraterone is a hormone-therapy tablet for prostate cancer that has spread and is still being driven by male hormones (androgens). It is used for metastatic castration-resistant prostate cancer and for newly diagnosed high-risk metastatic hormone-sensitive prostate cancer, always alongside a low dose of a steroid (prednisone or prednisolone) and usually while testosterone-lowering treatment continues.

Prostate cancer cells feed on testosterone. Standard hormone treatment stops the testicles making it, but the adrenal glands and the tumour itself can still produce small amounts. Abiraterone blocks the enzyme that makes androgens everywhere in the body, cutting off that remaining supply.

It is taken once a day on an empty stomach. Blood pressure, potassium and liver function are checked regularly because blocking androgen production also affects other adrenal hormones — which is why the steroid is prescribed with it. Abiraterone is a prescription-only medicine; a valid prescription must be provided at checkout.

How it works

How does Abiraterone work?

Androgens such as testosterone are made from cholesterol through a chain of enzyme steps. One of those steps needs an enzyme called CYP17A1, which is active in the testicles, the adrenal glands and in prostate tumour cells themselves. Abiraterone blocks CYP17A1, so androgen production drops sharply throughout the body — not only in the testicles — and the cancer loses the hormone signal it depends on. Because the same enzyme sits on the pathway to cortisol, the body compensates by making more of a related hormone that raises blood pressure and lowers potassium; the small steroid dose taken with abiraterone prevents that.

Enzyme blockade

Abiraterone irreversibly inhibits CYP17A1 (17α-hydroxylase / C17,20-lyase), the enzyme needed to convert precursors into androgens.

Androgen starvation

Testosterone from the adrenal glands and from within the tumour falls to very low levels, removing the signal that drives androgen-receptor-positive prostate cancer.

Steroid balance

Blocking CYP17A1 also lowers cortisol, so ACTH rises and pushes up mineralocorticoids; the co-prescribed prednisone/prednisolone suppresses ACTH and prevents fluid retention, low potassium and high blood pressure.

Uses

What is Abiraterone used for?

Metastatic castration-resistant prostate cancer (mCRPC)

With prednisone or prednisolone, before or after chemotherapy with docetaxel.

FDA EMA CDSCO
Metastatic high-risk castration-sensitive prostate cancer (mCSPC / mHSPC)

With prednisone/prednisolone and androgen-deprivation therapy, in newly diagnosed high-risk disease.

FDA EMA CDSCO

Only your oncologist can determine whether this medicine is right for your diagnosis. The above is for information only.

Dosage

How to take Abiraxen 250mg Tablets

Your oncologist will prescribe your exact dose. The right dose for you depends on your weight, kidney and liver function, and — for some medicines — your genetic test results.

Always take exactly as prescribed. Do not change your dose or stop taking this medicine without speaking to your doctor first, even if you feel well.

Missed a dose? If you miss a whole day, take your usual dose the next day. Never take two days' doses at once. Do not miss the steroid either — tell your team if you miss more than one day.

With food? Take on an empty stomach — no food for at least two hours before and one hour after. Food increases absorption up to ten-fold and makes side effects unpredictable. Swallow whole with water.

Important safety information

Safety & warnings

Please read this section before taking Abiraxen 250mg Tablets and discuss any concerns with your oncologist.

Common side effects

Side effects affect some people, not everyone. Most are manageable — let your treatment team know about anything that concerns you.

  • Tiredness (fatigue)
  • Joint swelling or discomfort
  • Swelling of legs or feet (fluid retention)
  • Hot flushes
  • Raised blood pressure
  • Low potassium
  • Diarrhoea, indigestion
  • Urinary tract infection
  • Raised liver enzymes

Contact your doctor immediately if you notice:

  • Yellow skin or eyes, dark urine, severe tiredness, pain under the right ribs Stop and contact your oncologist immediately — possible liver injury; monitored by regular blood tests.
  • Palpitations, muscle weakness or cramps, severe dizziness Seek urgent review — possible low potassium or a heart-rhythm problem.
  • Severe headache, confusion, chest pain, breathlessness Seek emergency care — possible dangerously high blood pressure, heart problem or fluid on the lungs.
  • Extreme weakness, vomiting, low blood pressure, especially when unwell or if the steroid is stopped Seek urgent care — possible adrenal insufficiency; never stop the steroid abruptly.
  • Black or bloody stools, vomiting blood Seek emergency care.
  • A fall or a bone that breaks easily Tell your team; bone density can fall on long-term hormone therapy.

Important: tell your doctor about these medicines

Taking Abiraterone with certain other medicines can be dangerous. Always tell every doctor, dentist, and pharmacist about all medicines you are taking.

  • Strong CYP3A4 inducers (rifampicin, phenytoin, carbamazepine, phenobarbital, St John's wort) Major

    Reduce abiraterone levels substantially.

  • CYP2D6 substrates with a narrow margin (thioridazine, dextromethorphan, some antidepressants and beta-blockers) Major

    Abiraterone strongly inhibits CYP2D6 and can raise their levels.

  • Medicines that lower potassium or prolong the QT interval (diuretics, some antibiotics, antiarrhythmics) Major

    Additive risk of low potassium and heart-rhythm problems.

Pregnancy & breastfeeding

Abiraterone is not indicated for women and can harm an unborn baby. Women who are or may become pregnant should not handle the tablets without gloves.

Not applicable — not for use in women.

Abiraterone may reduce fertility in men. Discuss sperm banking before starting if this matters to you.

For full prescribing information see: FDA prescribing information: Zytiga (abiraterone acetate) — DailyMed

Storage

How to store Abiraxen 250mg Tablets

Temperature

Store at 20–25°C (68–77°F).

Light & moisture

Keep in the original bottle, tightly closed.

Keep away from children

Keep out of the sight and reach of children.

Safe handling

Hormonal anticancer medicine: swallow whole, do not crush; wash hands after handling. Women who are or could be pregnant should not handle broken tablets. Return unused tablets to a pharmacy.

Travelling

Carry in the original bottle with your prescription and an oncologist's letter, and keep your steroid with it — the two are taken together.

Reviewed for accuracy

Medically reviewed content

A. Srinivasan

A. Srinivasan

B.Pharm, M.Pharm

A. Srinivasan is a licensed clinical pharmacist with 24 years of experience. He holds a B.Pharm and M.Pharm from University of Madras. At OnlineMeds, he reviews medicine and health content to help ensure it is accurate, evidence-based, and easy to understand.

Our commitment to you

How we support oncology patients

We understand that accessing the right cancer medicine can feel overwhelming. Here is what you can expect from us.

Personal oncology support

Every enquiry is reviewed by our oncology doctor and pharmacist team — not an automated system.

Genuine, verified medicine

Sourced exclusively from licensed pharmaceutical manufacturers. Every batch is traceable from origin to your door.

Prescription checked before dispatch

We verify every prescription with our internal medical team. No shortcuts, no exceptions.

Cold-chain logistics

Temperature-sensitive medicines shipped with appropriate packaging to maintain integrity.

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No pharmacy branding or product name on the outer packaging.

Up to 80% less than branded

Generic oncology medicines contain the same active ingredient as the originator brand — at a fraction of the cost.

FAQ

Frequently asked questions

Is Abiraterone Acetate the same as Zytiga?

Abiraterone Acetate is the active ingredient in Zytiga. A generic Abiraterone Acetate medicine contains the same active ingredient at the same strength and is taken the same way — the main difference is cost. Always use it as prescribed by a licensed medical professional.

Why do I have to take a steroid with Abiraxen 250mg Tablets?

Blocking androgen production also lowers cortisol, and the body responds by making more of a hormone that raises blood pressure, causes fluid retention and lowers potassium. A small daily dose of prednisone or prednisolone prevents that. It is part of the treatment, not optional — and it must never be stopped suddenly.

[1] FDA prescribing information: Zytiga (abiraterone acetate) — DailyMed

Why on an empty stomach?

Food increases the amount of abiraterone absorbed — up to ten times with a fatty meal — so the approved dose was studied fasting. Leave two hours after eating and one hour before eating again.

[1] FDA prescribing information: Zytiga (abiraterone acetate) — DailyMed

Is Abiraxen 250mg Tablets chemotherapy?

No. It is a hormone therapy — it starves the cancer of testosterone rather than attacking dividing cells directly. Hair loss, sickness and low blood counts are not typical.

[2] NCI Drug Information: Abiraterone Acetate

Do I still need my hormone injections?

Usually yes. Abiraterone blocks androgens made by the adrenal glands and the tumour; the injections (or surgery) deal with the testicles. Your oncologist will tell you whether to continue — most people do.

[1] FDA prescribing information: Zytiga (abiraterone acetate) — DailyMed

Why are my blood pressure and potassium checked so often?

They are the side effects the steroid is there to prevent, and they can still occur. Blood pressure, potassium and fluid retention are checked at least monthly; liver tests every two weeks for the first three months. It is routine, and most changes are managed easily.

[1] FDA prescribing information: Zytiga (abiraterone acetate) — DailyMed

Is Abiraxen 250mg Tablets the same as Zytiga?

Abiraxen 250mg Tablets contains the same active ingredient, abiraterone acetate, at the same 250 mg strength as the originator brand Zytiga. Generic medicines must meet the same regulatory standards for quality, safety and effectiveness. Used as prescribed by a licensed medical professional.

[3] EMA: Zytiga — European public assessment report

Can my wife or daughter handle the tablets?

Women who are, or could become, pregnant should not handle abiraterone tablets without gloves, and nobody should handle broken tablets. Keep them in the original bottle.

[1] FDA prescribing information: Zytiga (abiraterone acetate) — DailyMed

Do I need a prescription to order Abiraxen 250mg Tablets?

Yes. Abiraterone is prescription-only. Upload your oncologist's prescription at checkout; our pharmacist team reviews it before dispatch. Used as prescribed by a licensed medical professional.

Sources

References

  1. 1. FDA prescribing information: Zytiga (abiraterone acetate) — DailyMed. https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=zytiga U.S. National Library of Medicine. Accessed 13 Sep 2026.
  2. 2. NCI Drug Information: Abiraterone Acetate. https://www.cancer.gov/about-cancer/treatment/drugs/abirateroneacetate National Cancer Institute. Accessed 13 Sep 2026.
  3. 3. EMA: Zytiga — European public assessment report. https://www.ema.europa.eu/en/medicines/human/EPAR/zytiga European Medicines Agency. Accessed 13 Sep 2026.
  4. 4. Macmillan Cancer Support: Abiraterone (Zytiga). https://www.macmillan.org.uk/cancer-information-and-support/treatments-and-drugs/abiraterone Accessed 13 Sep 2026.
Medical disclaimer: This content is for informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a licensed healthcare professional — specifically your oncologist — before starting, changing, or stopping any medication. Information is based on NDA #202379, NCI Drug Information, and NHS patient information.
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