Duovir

Tablet

by Duovir

Duovir Tablets

Lamivudine

Duovir Tablets is a trusted medication containing Active Pharmaceutical Ingredient, designed for personal use under the guidance of a healthcare professional. Available for prescription-based international supply with discreet worldwide delivery.

Quick Facts

Active ingredient: Lamivudine
Form: Tablet
Indication: HIV-1 infection, Hepatitis B
Manufacturer: Duovir

This medicine is available to order. Contact us for current pricing and availability.

Secure SSL

Discreet Packaging

Lab Tested

Rx Verified

Overview

What is Lamivudine?

Lamivudine (3TC) is a nucleoside reverse transcriptase inhibitor (NRTI) used in combination antiretroviral therapy (ART) for HIV-1 and chronic Hepatitis B. It is one of the most widely used antiretrovirals globally and forms the backbone of many first-line ART regimens due to its tolerability and low resistance barrier as part of combination therapy.

Mechanism

How Does It Work?

Cellular conversion

Lamivudine enters infected cells and is phosphorylated to its active triphosphate form (3TC-TP) by cellular kinases.

Chain termination

3TC-TP competes with the natural substrate cytidine triphosphate, incorporating into viral DNA and causing premature termination of reverse transcription.

Dual activity

In HIV treatment, 3TC also suppresses Hepatitis B viral replication when co-infected, making it useful in HIV/HBV co-infection.

Dosage

How to Use

Timing

Once or twice daily depending on regimen

How to Take

Take with or without food. Swallow whole.

Frequency

Once or twice daily

With Food

No significant food interactions

Alcohol

Limit alcohol — may worsen liver stress in Hepatitis B patients

Missed Dose

Take as soon as remembered. If close to next dose, skip the missed dose. Never double dose.

Safety

Side Effects & Precautions

Common Side Effects

Headache
Nausea
Diarrhoea
Fatigue
Nasal symptoms

Serious Side Effects — seek help immediately

Lactic acidosis (rare but serious, especially in women)
Severe acute exacerbations of Hepatitis B on discontinuation
Pancreatitis in paediatric patients (rare)

Who Should Not Take This

Known hypersensitivity to lamivudine
Do not discontinue abruptly in HBV co-infected patients without monitoring

Value

Generic vs Brand

Generic (OnlineMeds)

Epivir / Lamivir

Price per unit

—

$150–$400/month

Active ingredient

Identical

WHO-GMP certified

✓

Bioequivalent

✓

Reference

Storage

Storage & Handling

Temperature

Below 25°C

Light

Keep in original packaging

Humidity

Store in a dry place

Children

Keep out of reach of children.

Why OnlineMeds

Why Buy From Us

Manufacturer Direct

Sourced directly from WHO-GMP certified manufacturers.

Quality Verified

Every batch tested for purity and bioequivalence.

Global Delivery

Discreet shipping to UK, US, AU, EU and beyond.

Licensed Pharmacy

Regulated and compliant with international pharmacy standards.

FAQ

Frequently Asked Questions

Is Duovir Tablets the same as 3TC?

Yes. Lamivudine is the generic name; 3TC is the common abbreviation. Both refer to the same medicine. It is widely available as a generic and as part of fixed-dose combination tablets.

Can I stop taking Duovir Tablets suddenly?

No. If you are co-infected with Hepatitis B, stopping lamivudine abruptly can trigger a serious flare of hepatitis. Always taper or substitute under medical supervision.

Does Lamivudine work alone for HIV?

No. Lamivudine must be used as part of combination antiretroviral therapy (at least 3 agents). Monotherapy rapidly leads to resistance due to a single M184V mutation.

What happens if I miss a dose of Duovir Tablets?

Take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular schedule. Do not double up.

⚠ BLACK BOX WARNING

Lactic acidosis and severe hepatomegaly with steatosis have been reported with NRTIs, including fatal cases.

Severe acute exacerbations of Hepatitis B have occurred after discontinuation in HBV-infected patients. Monitor hepatic function for several months.

Drug Interactions

Drug / Substance	Effect	Action
Emtricitabine (FTC)	Similar mechanism — do not combine (additive without benefit)	Avoid co-administration
Zalcitabine (ddC)	Mutual inhibition of intracellular phosphorylation	Avoid combination

Approved Indications

HIV-1 infection (adults and children) FDA / EMA
Chronic Hepatitis B in adults FDA / EMA

References

ViiV Healthcare. Epivir (lamivudine) prescribing information. ↗

Disclaimer: This content is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Used as prescribed by a licensed medical professional.

Duovir Tablets Order Now