by Emcure Pharmaceuticals Ltd.

Mofilet 250mg Tablets

Mycophenolate Mofetil 250 mg

Mofilet 250mg Tablets is a trusted medication containing Mycophenolate Mofetil, designed for personal use under the guidance of a healthcare professional. Available for prescription-based international supply with discreet worldwide delivery.

Quick Facts

Active ingredient: Mycophenolate Mofetil
Strength: 250 mg
Form: Tablet
Indication: Prevention of organ rejection after kidney, heart, or liver transplant
Manufacturer: Emcure Pharmaceuticals Ltd.

Commonly used forOrgan Transplant

This medicine is available to order. Contact us for current pricing and availability.

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Overview

What is Mycophenolate Mofetil?

Mycophenolate mofetil (MMF) is an immunosuppressant that prevents the body from rejecting a transplanted organ. It works by selectively blocking the proliferation of T and B lymphocytes — the main immune cells responsible for organ rejection — while largely sparing other cell types that can use an alternative purine synthesis route.

Mechanism

How Does It Work?

Prodrug conversion

MMF is rapidly hydrolysed to the active mycophenolic acid (MPA) after oral administration, which carries out the drug's immunosuppressive action.

IMPDH inhibition

MPA selectively inhibits inosine monophosphate dehydrogenase (IMPDH), the rate-limiting enzyme in the de novo purine synthesis pathway required for DNA replication.

Lymphocyte selectivity

T and B cells rely almost exclusively on de novo purine synthesis. IMPDH inhibition therefore selectively suppresses lymphocyte proliferation while other cells use the salvage pathway.

Dosage

How to Use

General guidance

1 g twice daily (kidney transplant, adult)
1.5 g twice daily (heart transplant, adult)
Take on an empty stomach; swallow whole — do not crush or chew

Take exactly as prescribed. Your prescriber's instructions replace the general guidance above.

Safety

Side Effects & Precautions

Common Side Effects

Diarrhoea
Nausea
Vomiting
Abdominal pain
Leukopenia
Increased susceptibility to infection

Serious Side Effects — seek help immediately

Severe neutropenia (high infection risk)
Progressive multifocal leukoencephalopathy (PML — rare but fatal)
Pure red cell aplasia
Lymphoma with prolonged immunosuppression

Who Should Not Take This

Pregnancy (teratogenic — Category D/X)
Hypersensitivity to MMF or mycophenolic acid

Value

Generic vs Brand

Generic (OnlineMeds)

CellCept

Price

—

$400–700/month (US list price)

Active ingredient

Identical

Licensed manufacturers

✓

Bioequivalent

✓

Reference

Medically reviewed by

Nicholas Brain B.Pharm, M.Pharm

Nicholas Brain is a licensed clinical pharmacist with 16 years of experience. He holds a B.Pharm and M.Pharm from Kannur University. At OnlineMeds, he reviews medicine and health content to help ensure it is accurate, evidence-based, and easy to understand.

Storage

Storage & Handling

Storage

Store at room temperature 15–30°C

Storage 2

Keep in original container away from moisture and light

Children

Keep out of reach of children.

Why OnlineMeds

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Sourced from licensed manufacturers through regulated supply channels.

Global Delivery

Discreet shipping to UK, US, AU, EU and beyond.

Licensed Pharmacy

Regulated and compliant with international pharmacy standards.

FAQ

Frequently Asked Questions

Why do I need Mofilet 250mg Tablets after my transplant?

Your immune system would normally attack a transplanted organ as foreign tissue. Mycophenolate Mofetil selectively suppresses the T and B cells responsible for rejection, allowing your new organ to function safely.

Can I stop taking Mofilet 250mg Tablets if I feel well?

No. Stopping Mycophenolate Mofetil without medical advice can trigger acute rejection within days, even years after transplant. Always consult your transplant team before any changes.

Is Mofilet 250mg Tablets safe during pregnancy?

No — Mycophenolate Mofetil is teratogenic and must be avoided in pregnancy. Use two forms of reliable contraception throughout treatment and for 6 weeks after stopping.

What infections should I watch for while taking Mofilet 250mg Tablets?

Bacterial, viral (CMV, BK virus), and fungal infections are more common. Report any fever, unusual fatigue, or respiratory symptoms to your doctor promptly.

⚠ BLACK BOX WARNING

Increased susceptibility to infection and possible development of lymphoma may result from immunosuppression. Only physicians experienced in immunosuppressive therapy should prescribe.

Use during pregnancy is associated with increased risk of pregnancy loss and congenital malformations. Females of reproductive potential must use effective contraception.

Drug Interactions

Drug / Substance	Effect	Action
Tacrolimus / ciclosporin (pharmacokinetic interaction)
Antacids / cholestyramine (reduce MPA absorption — separate doses)
Live vaccines (avoid during immunosuppression)
Rifampicin (reduces MPA exposure — avoid combination)

References

Disclaimer: This content is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Used as prescribed by a licensed medical professional.

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